Cellulose degrading bacteria were isolated from wide-ranging sources from marine habitats to herbivore residues and gastrointestinal region. Vibrio parahaemolyticus isolated from marine environment is capable of hydrolyzing CMC as well as U. in- testinalis and U. lactuca hydrolysate medium indicating presence of cellulase enzyme capable of hydrolyzing seaweed polysaccharides. Highest enzyme activity was recorded at 24 h and bacteria had salt tolerance up to 14% indicating its marine nature with total activity of 2.11 U/ml and specific activity of 6.05 U/mg. Enzyme hydrolysis for acid pretreated macroalgal biomass U. intestinalis and U. lactuca was carried out and 135.9 mg/g and 107.6 mg/g of reducing sugar was obtained respectively. The highlight of the current study is the enzyme extracted from salt tolerant Vibrio parahaemolyticus bacteria is suitable for optimal saccharification of seaweed polysaccharides towards biofuel production.