Changes in land use analysis show the decrease in forest cover over from 1985-2018 with increase in demand leading to demographic pressure with the shortage of natural resources. Anthropogenic activities like the developmental projects, which includes the railway lines, hydroelectric power projects etc. also add to degradation of natural resources, which have been increased in this vicinity of the biodiversity hotspot affecting the habitat of flora and fauna posing a serious threat to ecosystem. Land use analysis was done using supervised classification approach using Gaussian maximum likelihood algorithm. Overall accuracy of the classification varied from 80 % to 95% and kappa from 0.78 to 0.94. An increase of 3.81% in the built up activities is noticed, especially in the regions of Pune, Coimbatore etc. Agricultural activities have increased by 3.86%. Deforestation has led to forest loss, fragmentation and degradation of natural habitat causing threat to the ecosystem. The analysis showed the large scale conversion of natural habitat to man-made ecosystem. This necessitates an immediate action to curtail the insignificant activities by appropriate and sustainable management approaches.