ID: 65755
Title: Open Datasets of Faecal Sludge Characteristics
Author: BJ Ward,Stanley Sam,Linda Strande Nienke Andriessen
Editor: Paul Donahule and Christoph Luthi, Eawag
Year: 2022
Publisher: Eawag, 8600 Dubendorf, Switzerland
Source: ENVIS, CES & EWRG, CES
Reference: Sandec news, Issue No.23 9/22 21-21 (2022)
Subject: Open Datasets of Faecal Sludge Characteristics
Keywords: None
Abstract: Historically, information on the characteristics of faecal sludge has
been difficult to access or simply lacking. Faecal sludge characterisation
campaigns are resource intensive
and expensive.
Generating
quality
data
requires infrastructure,
experienced
technical
staff,
and
standard
methods,
which
are
only
recently
being
developed
for
faecal
sludge. The
Management of Excreta
Wastewater
and Sludge
(MEWS)
research
group
is
contributing
to
filling
this
information
gap
by
sharing open
data.
MEWS
has
produced
extensive
characterisation
of 850 faecal
sludge samples from Uganda, Vietnam,
Zambia,
India, Senegal, and Tanzania,
with an additional 212
characterisation
samples to be released next
year.
Location: T E 15 New Biology building
Literature cited 1: Englund M. et al., ‘Modelling quantities and qualities (Q&Q)
of f
aecal sludge in Hanoi, Vietnam and Kampala, Uganda for
improved management solutions’, Journal of Environmental
Management, 261, (2020) 110202.
Literature cited 2: Strande L. et al., ’Estimating quantities and qualities (Q&Q)
of f
aecal sludge at community to city-wide scales‘, in
Velkushanova K. et al. (eds), Methods for Faecal Sludge
Analysis. (IWA Publishing, 2021), 115
–
1
44.
ID: 65754
Title: A Technology Evaluation Tool for Effective Organic Waste Recovery
Author: Dorian Tosi Robinson, Adeline Mertenat, Christian Zurbrügg
Editor: Paul Donahule and Christoph Luthi, Eawag
Year: 2022
Publisher: Eawag, 8600 Dubendorf, Switzerland
Source: ENVIS, CES & EWRG, CES
Reference: Sandec news, Issue No.23 9/22 17-17(2022)
Subject: A Technology Evaluation Tool for Effective Organic Waste Recovery
Keywords: None
Abstract: Numerous options exist to treat organic waste – the highest share
of waste produced in low- and middle-income settings. From our
experience, a decision on which technology to use is often made
without evaluating the specific local context and knowing the full
spectrum of technology options. To overcome this knowledge gap
and support practitioners in making technology decisions, MSWM
developed the SOWATT – Selecting Organic Waste Treatment Technologies
decision support manual. SOWATT
helps in the identification
of the technical,
economic, and social parameters that
influence
the performance
of treatment technologies,
and assists
in
making comparisons and rankings among treatment options for
a
given
location.
Location: T E 15 New Biology building
Literature cited 1: Kaza S. et al., What a Waste 2.0: A Global Snapshot of Solid
Waste Management to 2050 (Washington, DC, World Bank,
2018).
Literature cited 2: Zabaleta I. et al., Selecting Organic Waste Treatment
Technologies: SOWATT (Eawag, Switzerland, 2020).
ID: 65753
Title: Food Waste Recycling at Household Level with Black Soldier Fly Larvae
Author: Saleha Mahmood Background sandec news 23 / 2022 , Christian Zurbrügg
Editor: Paul Donahule and Christoph Luthi, Eawag
Year: 2022
Publisher: Eawag, 8600 Dubendorf, Switzerland
Source: ENVIS, CES & EWRG, CES
Reference: Sandec news, Issue No.23 9/22 16-16 (2022)
Subject: Food Waste Recycling at Household Level with Black Soldier Fly Larvae
Keywords: None
Abstract: Food waste is the largest fraction of municipal household waste in
Pakistan. Whereas other waste types are scavenged and recycled
by the informal sector, food waste is currently not perceived as having
sufficient
economic value
to warrant
segregation. Therefore,
it
generally
ends up in the waste
bin, mixed
with other low
value
materials,
and is either disposed of indiscriminately in open spaces or
at
disposal sites, causing serious environmental
and health threats.
The
heterogeneous nutritious
nature
of household food
waste
makes
it an ideal feeding
substrate for
the growth
of Black
Soldier
Fly
Larvae
(BSFL). Recycling
food
waste
at household level
with
BSFL,
thereby
generating valuable
products, such
as protein rich
animal
feed
and soil conditioner,
can provide
a promising incentive
to
segregate food
waste
at source, relieve
the burden on waste
collection
services
by
diverting
organics from disposal sites and reduce
greenhouse gas emissions.
Location: T E 15 New Biology building
Literature cited 1: Diener S. et al., Opportunities and constraints for
medium-scale organic waste treatment with fly larvae
composting, (15
the
International Waste Management and
Landfill Symposium, 2015).
Literature cited 2: Mahmood S., ‘Sustainable Waste Management at
Household Level with Black Soldier Fly Larvae
(Hermetia illucens)’, Sustainability, 13/17, (2021) 9722.
ID: 65752
Title: Waste Flow Diagram: Identifying Waste Management System Leakages
Author: Christian Zurbrügg, Dorian Tosi Robinson, representing the WFD project team
Editor: Paul Donahule and Christoph Luthi, Eawag
Year: 2022
Publisher: Eawag, 8600 Dubendorf, Switzerland
Source: ENVIS, CES & EWRG, CES
Reference: Sandec news, Issue No.23 9/22 14-15 (2022)
Subject: Waste Flow Diagram: Identifying Waste Management System Leakages
Keywords: None
Abstract: Municipal solid waste management (MSWM) is a global challenge,
particularly impacting low- and middle-income countries, as recognised by its inclusion in the United Nations Sustainable Development Goals (SDG 11 “Sustainable cities and communities”).
Indicator 11.6.1 aims to monitor the “proportion of municipal solid
waste collected and managed in controlled facilities out of total municipal solid waste generated by cities”. Mismanaged waste has severe impacts both on human health and the environment, with one
rapidly emerging problem being plastic pollution.
Location: T E 15 New Biology building
Literature cited 1: WaCT Tool: https://unhabitat.org/wwc-tool
WFD user manual:
https://archive.researchdata.leeds.ac.uk/751/
Literature cited 2: ] WFD online tutorials:
https://www.youtube.com/watch?v=g_jLS2lMpqc and
https://www.youtube.com/watch?v=dCu6YaUANbY
ID: 65751
Title: South-South Knowledge Exchange for Plastic & Biomedical Waste Management
Author: Adeline Mertenat, Pia Hollenbach, Sudarshan Rajbhandari, Jayanthi TA, Babu Ambat, Damitha Samarakoon, René Véron, Christian Zurbrügg
Editor: Paul Donahule and Christoph Luthi, Eawag
Year: 2022
Publisher: Eawag, 8600 Dubendorf, Switzerland
Source: ENVIS, CES & EWRG, CES
Reference: Sandec news, Issue No.23 9/22 13-13 (2022)
Subject: South-South Knowledge Exchange for Plastic & Biomedical Waste Management
Keywords: None
Abstract: The Transformation Accelerating Grant (TAG) project entitled “Participatory Training 4 Sustainable Waste Governance: South-South Knowledge Transfer Program” is a one-year project that started in June 2021,
funded by the SNSF Research for Development (r4d) programme1.
This project grew out of an ongoing R4D project that started in November 2018 focusing on learning from post-crisis municipal solid waste
governance initiatives in South Asia2. The overarching objective of the
TAG project was to transfer and adapt successful waste technologies
and governance practices from Kerala, India, to the sociocultural and
political contexts in Nepal and Sri Lanka, using co-creation of knowledge, capacity building and local stakeholder involvement. As part of
the team, Sandec supported the knowledge exchange by providing
technical know-how and assisted coordination of the activities.
Location: T E 15 New Biology building
Literature cited 1:
Literature cited 2:
ID: 65750
Title: Assessing BSFL Bioconversion Efficiency on Ammonia Pretreated Cow Manure
Author: Daniela A. Peguero, Andrea Endara, Moritz Gold, Alexander Mathys, Christian Zurbrügg
Editor: Paul Donahule and Christoph Luthi, Eawag
Year: 2022
Publisher: Eawag, 8600 Dubendorf, Switzerland
Source: ENVIS, CES & EWRG, CES
Reference: Sandec news, Issue No.23 9/22 12-12 (2022)
Subject: Assessing BSFL Bioconversion Efficiency on Ammonia Pretreated Cow Manure
Keywords: None
Abstract: Black Soldier Fly Larvae (BSFL) transform agri-food wastes and byproducts into high quality nutrients for pet food, aquaculture, and animal feed, and leave behind a residue that can serve as a nutrient-rich
soil conditioner. However, one current drawback is their low conversion efficiency of these wastes and byproducts due to their high consistency of difficult to digest fibres, such as hemicellulose and lignin.
For example, cow manure can have high fibre content, with 12–21%
hemicellulose and 6–14% lignin (based on dry mass), making it difficult for larval or microbial decomposition . A previous study reported that larvae grown on cow manure resulted in a low bioconversion
rate of 4% compared to 15% when grown on nutritious food waste
(based on dry mass) . The conversion efficiency of cow manure
could potentially be improved by breaking down some fibres, using an
ammonia pretreatment prior to larval rearing ,
to facilitate larval or microbial degradation. Ammonia pretreatments
have been widely used for other bioconversion technologies, such as
anaerobic digestion, to improve the conversion of fibrous agri-food
wastes and byproducts into biogas . Therefore, this study evaluated
if ammonia pretreatment can improve cow manure bioconversion.
Location: T E 15 New Biology building
Literature cited 1: Peguero D.A. et al., ‘A Review of Pretreatment Methods
to Improve Agri-food Waste Bioconversion by Black Soldier
Fly Larvae’, Frontiers in Sustainable Food Systems, 5,
(2022) 1 – 9.
Literature cited 2: Gold M. et al., ‘Biowaste treatment with black soldier fly
larvae: Increasing performance through the formulation
of biowastes based on protein and carbohydrates’,
Waste Management, 102, (2020) 319 – 329
ID: 65749
Title: A Cost Assessment and Modelling Tool for Municipal Solid Waste Management
Author: Dorian Tosi Robinson, Adeline Mertenat, Carlos García, Eddy Lemus, Sergio Morales, Christian Zurbrügg
Editor: Paul Donahule and Christoph Luthi, Eawag
Year: 2022
Publisher: Eawag, 8600 Dubendorf, Switzerland
Source: ENVIS, CES & EWRG, CES
Reference: Sandec news, Issue No.23 9/22 8-9 (2022)
Subject: A Cost Assessment and Modelling Tool for Municipal Solid Waste Management
Keywords: None
Abstract: In low- and middle-income settings, limited financial resources, combined with low cost efficiency is often the cause for limited service
delivery. Although a large share of municipal budgets are used for
collection, street sweeping and disposal, the service quality generally remains low [1]. Municipalities and service providers often do not
monitor, assess and evaluate solid waste management expenditures, nor do they compare this with service performance indicators.
Fragmentation of expenditures amongst different administrative and
organisational units of municipalities, as well as unaccounted, hidden
costs, such as depreciation of infrastructure and equipment or use
of land, complicate efforts to obtain a comprehensive overview. To
support practitioners and municipalities in this regard, a collaboration
with Helvetas Bolivia led to the development of an Excel-based cost
assessment and modelling tool based on the work of Coffey and
Coad [2]. Adapted to low- and middle-income settings, the tool was
validated in three municipalities in Bolivia with 50,000–250,000 inhabitants. The tool guides the user through several steps to assess
the situation of waste management in terms of: 1) efficiency, 2)
costs and revenue, and 3) provides estimated costs from the modelling of four types of collection systems.
Location: T E 15 New Biology building
Literature cited 1: Kaza S. et al., What a Waste 2.0: A Global Snapshot of Solid
Waste Management to 2050, (World Bank, 2018).
Literature cited 2: Coffey M., Coad A., Collection of Municipal Solid Waste in
Developing Countries, (UN-Habitat, 2010).
ID: 65748
Title: Optimizing anaerobic digestion of tannery fleshings with different inoculums using biochemical methane potential test and mathematical modelling
Author: V. Kavan Kumar, R. Mahendiran , P. Subramanian , S. Karthikeyan , A. Surendrakumar , Y. Ravi , Sharda Choudhary , Ravindra Singh and Arvind K. Verma
Editor: S.K.Satheesh
Year: 2024
Publisher: Current Science Association and Indian Academy of Sciences.
Source: ENVIS, CES & EWRG, CES
Reference: Current Science Vol. 126 (4) 496-502 25 Feb (2024)
Subject: Optimizing anaerobic digestion of tannery fleshings with different inoculums using biochemical methane potential test and mathematical modelling
Keywords: Anaerobic digestion, biogas first-order kinetics, inoculums, tannery fleshings.
Abstract: The present experimental set-up study of tannery fleshings with different inoculum batch sizes, was carried
out for an hydraulic retention time of 50 days to check
the capability of anaerobic digestion. Biogas production
was between 10,102.5 and 14,505 ml/day. The firstorder and modified Gompertz models were calibrated
using experimental data. For kinetic analysis of biogas
production, modified Gompertz models and basic firstorder kinetics were employed. In each instance, the kinetic
parameters, substrate biogas yield potential, maximal
biogas production rate, lag phase time, coefficient of
determination and root mean square error were calculated. The model parameters were estimated using the
nonlinear regression approach made possible by IBM
SPSS software 25.0. Both the models fitted/predicted
the experimental data with over 99% accuracy (R2 =
0.990–0.999)
Location: T E 15 New Biology building
Literature cited 1: Costa, M. and Gutterres, M., Biogas from tannery solid waste
anaerobic digestion is driven by the association of the bacterial
order bacteroidales and archaeal family methanosaetaceae, 2020.
Rodríguez-Valderrama, S., Escamilla-Alvarado, C., Rivas-García,
P. and Magnin, J., Biorefinery concept comprising acid hydrolysis,
dark fermentation and anaerobic digestion for co-processing of fruit
and vegetable wastes and corn stover. No. i, 2020.
Literature cited 2: Lee, J., Hong, J., Jeong, S., Chandran, K. and Young, K., Bioresource technology interactions between substrate characteristics and
microbial communities on biogas production yield and rate.
Bioresour. Technol., 2020, 303, 122934; doi:10.1016/j.biortech.
2020.122934.
Membere, E. and Sallis, P., Effect of temperature on kinetics of
biogas production from macroalgae. Bioresour. Technol., 2018, 263,
410–417.
ID: 65747
Title: Dynamics of farm indebtedness in the agriculturally developed regions of India: a case of Cauvery Delta Zone across Tamil Nadu and Puducherry
Author: A. Pouchepparadjou , R. Jayakumara Varadan, S. Parthasarathi , M. Umamageswari and D. Cathrine
Editor: S.K.Satheesh
Year: 2024
Publisher: Current Science Association and Indian Academy of Sciences.
Source: ENVIS, CES & EWRG, CES
Reference: Current Science Vol. 126 (4) 486-495 25 Feb (2024)
Subject: Dynamics of farm indebtedness in the agriculturally developed regions of India: a case of Cauvery Delta Zone across Tamil Nadu and Puducherry
Keywords: Agrarian crisis, farm indebtedness, income inequality, institutional credit, skill development
Abstract: Tamil Nadu is one of India’s most agriculturally developed states, but has high-income inequality and indebtedness among its farmers. This study explores the
dynamics of farm indebtedness among farmers in the
Cauvery Delta Zone of combined Tamil Nadu state
and Puducherry Union Territory. Resonating with the
state-level trend, income inequality among the sampled
farm households is significantly high, with a Gini coefficient of 0.56, and it decreases with an increase in
farm size. Similarly, 80% of farmers are indebted,
with the incidence of indebtedness, extent of indebtedness and proportion of institutional loanees increasing
with farm size. Though all categories of farmers have
considerable access to institutional credit, large farmers can fulfil all their credit needs through institutional
sources, while small landholders have to fulfil almost
30% of their credit needs through non-institutional
sources. Elderly farmers, large landholders and farm
households with more dependent members are more
prone to indebtedness than their counterparts, while
farm households earning more income and possessing
more assets are less prone to indebtedness. Various
production, weather, market and institutional constraints deter farmers from repaying their outstanding
loans, resulting in a vicious cycle of indebtedness.
Therefore, farmers and youth of small farm households should improve their alternative employment
opportunities by utilizing the state-sponsored skill development programmes and enhance their financial
accessibility by availing Kisan Credit Cards.
Location: T E 15 New Biology building
Literature cited 1: Flachs, A., Charisma and agrarian crisis: authority and legitimacy
at multiple scales for rural development. J. Rural Stud., 2021, 88,
97–107; https://doi.org/10.1016/j.jrurstud.2021.10.010.
Patnaik, U., Global capitalism, deflation and agrarian crisis in developing countries. J. Agrar. Change, 2003, 3(1), 33–66.
Literature cited 2: Sharma, H. R. and Malik, S. H., Land distribution structure, marginalization of holdings and dimensions of viability crisis in Indian
agriculture: a state level analysis. Indian J. Agric. Econ., 2021,
76(2), 207–224.
Reddy, A. A., Raju, S. S. and Bose, A., Farmers’ income, indebtedness and agrarian distress in India. Microfinan. Rev., 2020, XII(1),
20–38
ID: 65746
Title: Predicting the intention to use an e-learning module on climate-smart horticulture
Author: Bai Koyu and Rajumar Josmee Singh
Editor: S.K.Satheesh
Year: 2024
Publisher: Current Science Association and Indian Academy of Sciences.
Source: ENVIS, CES & EWRG, CES
Reference: Current Science Vol. 126 (4) 478-485 25 Feb (2024)
Subject: Predicting the intention to use an e-learning module on climate-smart horticulture
Keywords: Agro-advisory services, climate–smart approach, e-learning module, farmers’ intention, horticulture, information and communication technology.
Abstract: The recent surge of information and communication
technologies (ICTs) has changed nearly every business,
including horticulture. Farmers can use climate information and ICT-based agro-advisory services to help
them make seasonal decisions, technology choices and
marketing strategies. Such drastic changes are upending traditional horticultural practices, and introducing
a plethora of new opportunities and challenges. This
study aimed to identify the factors influencing farmers’
intention to use an e-learning module. The study included
137 respondents from two districts in Arunachal Pradesh, North East India. The technology acceptance model
was used as a basis for the study. Dijkstra–Henseler’s
rho, Jöreskog’s rho, Cronbach’s alpha, average variance
extracted and Heterotrait–Monotrait ratio of correlations were used to assess the reliability and validity of
scale. ADANCO software was used to perform PLS–SEM,
which showed that facilitating conditions and subjective
norms had a significant positive effect on the intention
to use an e-learning module. The proposed model had
a good fit.
Location: T E 15 New Biology building
Literature cited 1: Singh, R. and Singh, G. S., Traditional agriculture: a climate smart
approach for sustainable food production. Energy Ecol. Environ.,
2017, 2(5), 296–316.
Park, S. Y., Kim, S.-W., Cha, S.-B. and Nam, M.-W., Comparing
learning outcomes of video-based e-learning with face-to-face lectures of agricultural engineering courses in Korean agricultural
high schools. Interact. Learn. Environ., 2014, 22(4), 418–428
Literature cited 2: Mutoko, M. C., Rioux, J. and Kirui, J., Barriers, incentives and
benefits in the adoption of climate-smart agriculture: lessons from
the MICCA pilot project in Kenya. Food and Agriculture Organization of the United Nations Rome, Italy, 2015; http://www.fao.org/3/
a-i4396e.pdf
Long, T. B., Blok, V. and Coninx, I., Barriers to the adoption and
diffusion of technological innovations for climate–smart agriculture
in Europe: evidence from the Netherlands, Food and Agricultural
Organization of United Nations, France, Switzerland and Italy.
J. Clean. Prod., 2016, 112, 9–21.
ID: 65745
Title: Cropping pattern and crop diversification in Kerala, India – a spatio-temporal analysis
Author: Shilpa Mathew, A. Prema and M. Hema
Editor: S.K.Satheesh
Year: 2024
Publisher: Current Science Association and Indian Academy of Sciences.
Source: ENVIS, CES & EWRG, CES
Reference: Current Science Vol. 126 (4) 470-477 25 Feb (2024)
Subject: Cropping pattern and crop diversification in Kerala, India – a spatio-temporal analysis
Keywords: Agro-ecological zones, constraints, crop diversification, cropping pattern, labour.
Abstract: The assessment of shift in cropping pattern is crucial
for a good insight into the agricultural development of
a region. The present study focused on the changes in
the cropping pattern and the extent of crop diversification
in Kerala, India. The results of the study revealed that
the share of food crops to the gross cropped area substantially declined from 56.85% in TE 1987–88 to
40.73% in TE 2019–20, whereas the share of non-food
crops increased remarkably from 43.14% in TE 1987–88
to 59.29% in TE 2019–20. The extent of crop diversification was higher in Idukki district, while crop specialization was prominent in Kozhikode district. Labour
unavailability, high labour wage rates and climate variability were identified as the major constraints faced by
the respondents in the study areas.
Location: T E 15 New Biology building
Literature cited 1: Mahesh, R., Causes and consequences of change in cropping pattern: location-specific study. Kerala Research Programme on Local
Level Development, Centre for Development Studies, Thiruvananthapuram, 1999, p. 56.
2. Khan, M. and Ahmad, A., Changing cropping pattern in Kheri district, Uttar Pradesh.
Literature cited 2: Singh, J. and Dilhon, S.S., Agricultural Geography, Tata McGraw
Hill Pub., New Delhi, 1987.
Seitinthang, Lh., Cropping pattern changes in Manipur. Hill Geogr.,
2013, 29(2), 1–8
ID: 65744
Title: Modelling of surface run-off using SWMM and GIS for efficient stormwater management
Author: Ram Suhawan Patel, Sonia Taneja, Jagdish Singh and Shashikant Nishant Sharma
Editor: S.K.Satheesh
Year: 2024
Publisher: Current Science Association and Indian Academy of Sciences.
Source: ENVIS, CES & EWRG, CES
Reference: Current Science Vol. 126 (4) 463-469 25 Feb (2024)
Subject: Modelling of surface run-off using SWMM and GIS for efficient stormwater management
Keywords: Educational campus, efficient management, regional approach, stormwater modelling, surface run-off
Abstract: The management of rainwater is of utmost importance
in the current climate change scenario. This study assesses
the current stormwater management of the Maulana
Azad National Institute of Technology (MANIT) campus,
Bhopal, Madhya Pradesh, India. It examines the efficiency
of the management system with the help of stormwater
management model (SWMM) and geographic information system (GIS) modelling. For this study, we
have adopted a regional approach (whole campus) of
MANIT for stormwater analysis. The quantitative interpretation of surface run-off analysis uses the SWMM
model and Arc-GIS at various outfall nodes and proposes planning interventions and strategies for sustainable stormwater management.
Location: T E 15 New Biology building
Literature cited 1: Choudhury, R. R. et al., Recognizing efforts and leadership in the
area of water management and conservation. Curr. Sci., 2017,
112(11), 2182–2183.
Bell, D., Reordering the World, Princeton University Press, Princeton,
NJ, USA, 2016.
Literature cited 2: Hanak, E. and Lund, J. R., Adapting California’s water management
to climate change. Clim. Change, 2012, 111(1), 17–44; doi:10.
1007/s10584-011-0241-3.
Sheng, J. and Wilson, J. P., Watershed urbanization and changing
flood behavior across the Los Angeles Metropolitan Region. Nat.
Hazards, 2009, 48(1), 41–57; doi:10.1007/s11069-008-9241-7
ID: 65743
Title: In silico design and molecular docking study of some novel flutamide analogues in the management of prostate cancer
Author: Ajay Kumar Gupta , Achal Mishra and Sanmati Kumar Jain
Editor: S.K.Satheesh
Year: 2024
Publisher: Current Science Association and Indian Academy of Sciences.
Source: ENVIS, CES & EWRG, CES
Reference: Current Science Vol. 126 (4) 452-462 25 Feb (2024)
Subject: In silico design and molecular docking study of some novel flutamide analogues in the management of prostate cancer
Keywords: Anti-androgen agent, bioisosteric approach, flutamide, molecular docking, prostate cancer
Abstract: The androgen receptor (AR) plays a crucial role in the
development of sexual functions in men, as well as the
overexpression of androgenic hormones that contribute
to prostate cancer (PC) development. Therefore, AR is
an essential target for PC research. The aryl group of
flutamide has been used as a replacement site in the
present study to design newer and safer analogues using a
bioisosteric approach with reduced toxicity. To design
flutamide analogues, MolOpt was used along with
ADMETlab 2.0 to determine their pharmacokinetic and
toxicity properties. Additionally, OSIRIS Property
Explorer was used to eliminate drug-likeness and drug
score. Docking of the newly designed analogues was carried out using ArgusLab 4.0.1 based on Hartree–Fock
calculations. The docking score ranged from –8.12 to
–11.06 kcal/mol for all the ligands. A good binding score
was observed for ligands 008, 009, 012, 016, 018 and
020, which had significantly better binding features than
the other ones. Results from the in silico approaches
(docking and ADMET study) suggest that these compounds 008 and 020 may have the potential as anti-androgen for prostate cancer. The hypothesis may be tested
by synthesizing and evaluating the compounds for antiandrogen activity using in vitro and in vivo approaches.
Location: T E 15 New Biology building
Literature cited 1: Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram,
I., Jemal, A. and Bray, F., Global cancer statistics 2020: Globocan
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA: Cancer J. Clin., 2021, 71, 209–249; https://doi.
org/10.3322/caac.21660.
Gunther, J. R., Parent, A. A. and Katzenellenbogen, J. A., Alternative inhibition of androgen receptor signaling: peptidomimetic pyrimidines as direct androgen receptor/coactivator disruptors. ACS
Chem. Biol., 2009, 4(6), 435–440; https://doi.org/10.1021/cb900043e
Literature cited 2: Yamada, A., Fujii, S., Mori, S. and Kagechika, H., Design and synthesis of 4-(4-benzoylaminophenoxy)phenol derivatives as androgenreceptor antagonists. ACS Med. Chem. Lett., 2013, 4(10), 937–941;
https://doi.org/10.1021/ml4001744.
Liu, H. L., Zhong, H. Y., Song, T. Q. and Li, J. Z., A molecular
modeling study of the hydroxyflutamide resistance mechanism induced by androgen receptor mutations. Int. J. Mol. Sci., 2017, 18,
1823; https://doi.org/10.3390/ijms18091823.
ID: 65742
Title: Impact of pharmaceutical toxicity on the environment and its regulatory aspects
Author: K. Venkateswara Raju, T. Harini, V. Akshaya Ratna Kireeti, A. Sai Priya and Lakshmi Prasanthi Nori
Editor: S.K.Satheesh
Year: 2024
Publisher: Current Science Association and Indian Academy of Sciences.
Source: ENVIS, CES & EWRG, CES
Reference: Current Science Vol. 126 (4) 442-451 25 Feb (2024)
Subject: Impact of pharmaceutical toxicity on the environment and its regulatory aspects
Keywords: Antimicrobial resistance, drug residues, environmental toxicity, green prescription, pharmaceutical pollutants
Abstract: Pharmaceutical-induced environmental contamination
demands urgent attention, with around 43% of global
rivers facing risks from active pharmaceutical ingredients (APIs). The entire spectrum of pharmaceutical
products, including active and inactive components,
requires serious consideration due to continuous emissions and potential hazards to the environment and
human health. Discussions on chemical waste reduction
face limitations due to incomplete knowledge about
their toxicity to humans. Despite various initiatives,
collaboration evidence is minimal, and environmental
health disparities persist in socially disadvantaged
communities, leading to higher disease rates. While
awareness of ecotoxicity is growing, the European Union
(EU), United States (US) and Canada have taken steps,
including disposal procedures, prevention strategies,
and focus on concerns like antimicrobial resistance.
This article explores environmental pollution complexities and policies in US, EU and Canada to mitigate its
impact within health disparities.
Location: T E 15 New Biology building
Literature cited 1: Drishti, I. A. S., Pharmaceutical pollution; https://www.drishtiias.
com/daily-updates/daily-news-analysis/pharmaceutical-pollution (retrieved on 31 January 2024).
US EPA, O. What are hazardous air pollutants? 2015; https://
epa.gov/haps/what-are-hazardous-air-pollutants.
Literature cited 2: Non-hazardous contaminants. Safeopedia. 28 April 2018; https://
www.safeopedia.com/definition/6778/non-hazardous-contaminants
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ID: 65741
Title: Performance of human–wildlife conflicts compensation scheme in Karnataka, India
Author: Naveen Kumar Naik, P. Venkatesh, D. R. Singh, Alka Singh, G. K. Jha, V. Sangeetha, D. K. Sharma and M. Balasubramanian
Editor: S.K.Satheesh
Year: 2024
Publisher: Current Science Association and Indian Academy of Sciences.
Source: ENVIS, CES & EWRG, CES
Reference: Current Science Vol. 126 (4) 434-441 25 Feb (2024)
Subject: Performance of human–wildlife conflicts compensation scheme in Karnataka, India
Keywords: Compensation scheme, constraints, human–wildlife conflicts, national park, performance.
Abstract: Compensation serves as a post-conflict management tool for human–wildlife conflicts. In the Bannerghatta National Park (BNP) region, Karnataka, India, around 57.4% and 95% of the farmers received compensation for crop loss and cattle kill respectively. Compensation claims incurred
transportation and paper costs of 60–70% and 30–40% respectively, and it took 7.6–12.3 months on
average to receive compensation. Crop loss applications had the lion’s share of the total applications, while the compensation paid share was relatively less in the total compensation paid. Inadequacy of compensation was a major constraint. Separate advance fund provisions for crop loss,
livestock depredation, property damage and human-related losses in proportion to annual cases can
prevent the delay and inadequacy of compensation.
Location: T E 15 New Biology building
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