Abstract: Ethnobotanical research in folk-lore medicine has been csrried out in Coimgbatore district of Tamilnadu and Plaghat district of Kerala. Of the assembly of the 20 remedies for jaundice, two were found to be new reports and a few others showed interesting combinations. The specimens were identified at the Botanical Survey of India, coimbatore, and deposited in the herbarium of the ethnobiology Department of the International Instute of Ayurveda, Coimbatore. Two newly reported plants for jaundice, namely Alysicarpus vaginalis DC. and Justicia tranquebariensis Lf., have been taken for the phytochemical studies. The botanical name, and part of the plant employed are tabulated in the report.